Nanoformulation of synergistic TLR ligands to enhance vaccination against Entamoeba histolytica
نویسندگان
چکیده
منابع مشابه
Monoclonal antibodies directed against the galactose-binding lectin of Entamoeba histolytica enhance adherence.
The Entamoeba histolytica galactose-binding lectin is a surface glycoprotein composed of 170- and 35-kDa subunits. Inhibition of this lectin with galactose or anti-170 kDa subunit polyclonal antibody blocks amebic adherence to target cells and colonic mucin glycoproteins. We describe the properties of 10 mAb with specificity for the 170-kDa subunit. Based on competitive binding studies, six non...
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We describe the pathology of a unique case of Fallopian tube amebiasis, associated with hydrosalpinx, in a 21-year-old woman. She complained of lower abdominal pain, had a foul-smelling green vaginal discharge and fever during one week. There was a discrete increase in body temperature and a painful abdominal palpation at the lower right side, with signs of local peritoneal irritation. Patholog...
متن کاملAppendicitis Due to Entamoeba Histolytica
While symptoms simulating appendicitis may occur in amoebic infections without the appendix being involved, a good proportion of patients exhibiting such symptoms actually are suffering from an invasion of the appendix by the parasite and the inflammatory condition of the organ brought about by such invasion. The following is an interesting case note of appendicitis due to E. histolytica. In Au...
متن کاملThe cultivation of entamoeba histolytica in HSr+ s medium
In 1926 for the first time Dobell and laid low synthesized and used Hsre+ s ( horse serum, ringer, egg+ starch rice) as a culture medium for growth of E.histolytica. since then this medium along with tens of other media have been used for growth of E.histolytica and other intestinal microorganisms. This medium has been used worldwide in many diagnostic and research laboratories. In Iran, in ...
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It has been suggested that two distinct species exist within what was originally known as Entamoeba histolytica and E. dispar. These are Entamoeba dispar for the nonpathogenic and E. histolytica for the pathogenic fonn. Differentiation of these two organisms is of great clinical importance since they are morphologically indistinguishable and both fonns can infect the human intestinal cavity...
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ژورنال
عنوان ژورنال: Vaccine
سال: 2017
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2016.12.057